I qualified in medicine from the University of Oxford in 1986. After a series of posts in internal medicine I worked for a year in Malawi on a leprosy vaccine trial. I then completed my training in public health medicine before taking up a post as research fellow in the CRC Human Cancer Genetics group at the University of Cambridge in 1996. Having completed my doctoral studies in 1999 I won a Cancer Research UK Senior Clinical Research Fellowship in 2004 my fellowship was renewed. On completion of my fellowship in 2009 I was appointed Reader in Cancer Epidemiology and promoted to a personal Chair in 2012, Department of Public Health and Primary Care, University of Cambridge.
My major research interests are i) common genetic variation and breast and ovarian cancer susceptibility and ii) the role of germline genotype in determining the clinical and molecular pathological characteristics of breast and ovarian cancer.